A software tool to automate VMAT treatment planning

Authors

DOI:

https://doi.org/10.37004/sefm/2023.24.1.002

Keywords:

VMAT, Automatic radiotherapy planning, ESAPI

Abstract

An in-house software to automate the volumetric modulated arc therapy treatment planning using the Varian Eclipse radiotherapy planning system is presented. It performs the entire planning process with very little human interaction. It interprets the clinical prescription and translates it into optimization objectives, creates auxiliary anatomical contours, and optimizes the plan to achieve proper dose distributions. The application allows the simultaneous processing of several plans.

To evaluate the performance of the software, several already treated plans from different anatomical localizations were randomly chosen, re-planned using this automated tool and compared. The difference between planned and prescribed dose was studied for all dose constraints. Automated plans obtained better results in more than half the prescribed dose limits for almost all locations.

The total time required to carry out the plans was also determined. It can be concluded that automated planning is quick and take less time than manual planning in most cases, but the main point is that automatic planning requires almost no human attention.

Automatic treatment planning can free up many staff hours, reduce the experience required, smooth the learning curve for this complex technique, decrease the subjective decisions and therefore increase the homogeneity in patient treatments.

References

T. Landberg, J. Chavaudra, J. Dobbs, J. -P. Gerard, G. Hanks, J. -C. Horiot, K. -A. Johansson, T. Möller, J. Purdy, N. Suntharalingam, H. Svensson. Report 62, Journal of the International Commission on Radiation Units and Measurements, Volume os32, Issue 1, 1 November 1999, Page NP, https://doi.org/10.1093/jicru/os32.1.Report62

Nutting C., Dearnaley DP., Webb S. Intensity modulated radiation therapy: a clinical review. Br J Radiol 2000; 73: 459–69, https://doi.org/10.1259/bjr.73.869.10884741

Chiavassa S, Bessieres I, Edouard M, Mathot M, Moignier A. Complexity metrics for IMRT and VMAT plans: a review of current literature and applications. Br J Radiol 2019; 92, https://doi.org/10.1259/bjr.20190270

Teoh M, Clark CH, Wood K, Whitaker S, and Nisbet A. Volumetric modulated arc therapy: a review of current literature and clinical use in practice. Br J Radiol 2011; 84: https://doi.org/10.1259/bjr/22373346

Otto K. Volumetric modulated arc therapy: IMRT in a single gantry arc. Med Phys 2008;35:310–7. 6. Daliang Cao et al. A generalized inverse planning tool for volumetric-modulated arc therapy. Phys. Med. Biol. 2009; 54, 21. doi:10.1088/0031-9155/54/21/018

Infusino E., Clinical utility of RapidArc™ radiotherapy technology. Cancer Manag Res. 2015; 7: 345–356. doi: 10.2147/ CMAR.S72775

Jurado-Bruggeman D., Hernández V., Sáez J., Navarro D., Pino F., Martínez T., Alayrach M., Ailleres N., Melero A., Jornet N., Multi-centre audit of VMAT planning and pre-treatment verification, Radiotherapy and Oncology, Volume 124, Issue 2, 2017, Pages 302-310, https://doi.org/10.1016/j.radonc.2017.05.019.

Hussein M, Heijmen BJM, Verellen D, Nisbet A. Automation in intensity modulated radiotherapy treatment planning—a review of recent innovations. Br J Radiol 2018; 91, https://doi.org/10.1259/bjr.20180270

Tol JP., Delaney AR., Dahele M., Slotman BJ, Verbakel W.,Evaluation of a Knowledge-Based Planning Solution for Head and Neck Cancer, IJROBP Vol 91, Issue 3, 2015, Pages 612-620, https://doi.org/10.1016/j.ijrobp.2014.11.014.

Kubo K., Monzen H., Ishii K., Tamura M., Kawamorita K., Sumida I., Mizuno H., Nishimura Y., Dosimetric comparison of RapidPlan and manually optimized plans in volumetric modulated arc therapy for prostate cancer, Physica Medica, Vol 44, 2017, Pages 199-204, https://doi.org/10.1016/j.ejmp.2017.06.026.

Cilla, S., Ianiro, A., Romano, C. et al. Template-based automation of treatment planning in advanced radiotherapy: a comprehensive dosimetric and clinical evaluation. Sci Rep 10, 423 (2020). https://doi.org/10.1038/s41598-019-56966-y

P. Xia, E. Murray, 3D treatment planning system—Pinnacle system, Medical Dosimetry 43 (2018) 118–128

Kierkels, R. G. J., Visser, R. & Bijl, H. P. Multicriteria optimization enables less experienced planners to efficiently produce high quality treatment plans in head and neck cancer radiotherapy. Radiat Oncol. 87(10) (2015).

Buschmann, M. et al. Advanced optimization methods for whole pelvic and local prostate external beam therapy. Phys.Med. 32, 465–73 (2016).

Della Gala, G., Dirkx, M.L.P., Hoekstra, N. et al. Fully automated VMAT treatment planning for advanced-stage NSCLC patients. Strahlenther Onkol 193, 402–409 (2017). https://doi.org/10.1007/s00066-017-1121-1

Voet P., Dirkx M., Breedveld S., Fransen D., Levendag P., Heijmen B., Toward Fully Automated Multicriterial Plan Generation: A Prospective Clinical Study, IJROBP, Vol 85, Issue 3, 2013, Pages 866-872, https://doi.org/10.1016/j.ijrobp.2012.04.015.

J. Pyyry & W. Keranen (Eds.). Varian APIs, a handbook for programming in the Varian oncology software ecosystem. First edition v.0.9.0, July 2018, https://varianapis.github.io

Levenshtein, V. I. Binary Codes Capable of Correcting Deletions, Insertions and Reversals. Soviet Physics Doklady (1966), Vol. 10, p.707 Jim P. Tol, Max Dahele, Jarkko Peltola, Janne Nord, Ben J. Slotman, Wilko FAR Verbakel. Automatic interactive optimization for volumetric modulated arc therapy planning. Radiation Oncology (2015) 10:75. doi: https://doi.org/10.1186/s13014-015-0388-6.

Vanetti E, Nicolini G, Nord J, Peltola J, Clivio A, Fogliata A, et al. On the role of the optimization algorithm of RapidArc(®) volumetric modulated arc therapy on plan quality and efficiency. Med Phys. 2011;38:5844–56. https://doi.org/10.1118/1.3641866.

Hernandez V, Hansen CR, Widesott L, Bäck A, Canters R, Fusella M, Götstedt J, Jurado-Bruggeman D, Mukumoto N, Kaplan LP, Koniarová I, Piotrowski T, Placidi L, Vaniqui A, Jornet N. What is plan quality in radiotherapy? The importance of evaluating dose metrics, complexity, and robustness of treatment plans. Radiother Oncol. 2020 Dec;153:26-33. doi:10.1016/j.radonc.2020.09.038.

Downloads

Published

2023-05-18

Issue

Section

Scientific articles

How to Cite

A software tool to automate VMAT treatment planning. (2023). Revista De Física Médica, 24(1), 29-42. https://doi.org/10.37004/sefm/2023.24.1.002
Bookmark and Share

Similar Articles

11-20 of 49

You may also start an advanced similarity search for this article.